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Common and well‐documented HLA alleles: 2012 update to the CWD catalogue

Identifieur interne : 000212 ( Main/Exploration ); précédent : 000211; suivant : 000213

Common and well‐documented HLA alleles: 2012 update to the CWD catalogue

Auteurs : S. J. Mack [États-Unis] ; P. Cano [États-Unis] ; J. A. Hollenbach [États-Unis] ; J. He [République populaire de Chine] ; C. K. Hurley [États-Unis] ; D. Middleton [Royaume-Uni] ; M. E. Moraes [Brésil] ; S. E. Pereira [États-Unis] ; J. H. Kempenich [États-Unis] ; E. F. Reed [États-Unis] ; M. Setterholm [États-Unis] ; A. G. Smith [États-Unis] ; M. G. Tilanus [Pays-Bas] ; M. Torres [Brésil] ; M. D. Varney [Australie] ; C. E. M. Voorter [Pays-Bas] ; G. F. Fischer [Autriche] ; K. Fleischhauer [Italie] ; D. Goodridge [Australie] ; W. Klitz [États-Unis] ; A. Little [Royaume-Uni] ; M. Maiers [États-Unis] ; S. G. E. Marsh [Royaume-Uni] ; C. R. Müller [Allemagne] ; H. Noreen [États-Unis] ; E. H. Rozemuller [Pays-Bas] ; A. Sanchez-Mazas [Suisse] ; D. Senitzer [États-Unis] ; E. Trachtenberg [États-Unis] ; Marcelo Fernandez-Vina [États-Unis]

Source :

RBID : ISTEX:3705D4F6302854FBF781F1A62CA149F9E22734B2

Abstract

We have updated the catalogue of common and well‐documented (CWD) human leukocyte antigen (HLA) alleles to reflect current understanding of the prevalence of specific allele sequences. The original CWD catalogue designated 721 alleles at the HLA‐A, ‐B, ‐C, ‐DRB1, ‐DRB3/4/5, ‐DQA1, ‐DQB1, and ‐DPB1 loci in IMGT (IMmunoGeneTics)/HLA Database release 2.15.0 as being CWD. The updated CWD catalogue designates 1122 alleles at the HLA‐A, ‐B, ‐C, ‐DRB1, ‐DRB3/4/5, ‐DQA1, ‐DQB1, ‐DPA1 and ‐DPB1 loci as being CWD, and represents 14.3% of the HLA alleles in IMGT/HLA Database release 3.9.0. In particular, we identified 415 of these alleles as being ‘common’ (having known frequencies) and 707 as being ‘well‐documented’ on the basis of ~140,000 sequence‐based typing observations and available HLA haplotype data. Using these allele prevalence data, we have also assigned CWD status to specific G and P designations. We identified 147/151 G groups and 290/415 P groups as being CWD. The CWD catalogue will be updated on a regular basis moving forward, and will incorporate changes to the IMGT/HLA Database as well as empirical data from the histocompatibility and immunogenetics community. This version 2.0.0 of the CWD catalogue is available online at cwd.immunogenomics.org, and will be integrated into the Allele Frequencies Net Database, the IMGT/HLA Database and National Marrow Donor Program's bioinformatics web pages.

Url:
DOI: 10.1111/tan.12093


Affiliations:


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<name sortKey="Senitzer, D" sort="Senitzer, D" uniqKey="Senitzer D" first="D." last="Senitzer">D. Senitzer</name>
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<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>HLA Laboratory, City of Hope, CA, Duarte</wicri:regionArea>
<wicri:noRegion>Duarte</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Trachtenberg, E" sort="Trachtenberg, E" uniqKey="Trachtenberg E" first="E." last="Trachtenberg">E. Trachtenberg</name>
<affiliation wicri:level="1">
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center for Genetics, Children's Hospital Oakland Research Institute, CA, Oakland</wicri:regionArea>
<wicri:noRegion>Oakland</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Fernandez Ina, Marcelo" sort="Fernandez Ina, Marcelo" uniqKey="Fernandez Ina M" first="Marcelo" last="Fernandez-Vina">Marcelo Fernandez-Vina</name>
<affiliation wicri:level="1">
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Pathology, Stanford University, CA, Stanford</wicri:regionArea>
<wicri:noRegion>Stanford</wicri:noRegion>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series>
<title level="j">Tissue Antigens</title>
<title level="j" type="abbrev">Tissue Antigens</title>
<idno type="ISSN">0001-2815</idno>
<idno type="eISSN">1399-0039</idno>
<imprint>
<publisher>Blackwell Publishing Ltd</publisher>
<pubPlace>Oxford, UK</pubPlace>
<date type="published" when="2013-04">2013-04</date>
<biblScope unit="volume">81</biblScope>
<biblScope unit="issue">4</biblScope>
<biblScope unit="page" from="194">194</biblScope>
<biblScope unit="page" to="203">203</biblScope>
</imprint>
<idno type="ISSN">0001-2815</idno>
</series>
<idno type="istex">3705D4F6302854FBF781F1A62CA149F9E22734B2</idno>
<idno type="DOI">10.1111/tan.12093</idno>
<idno type="ArticleID">TAN12093</idno>
</biblStruct>
</sourceDesc>
<seriesStmt>
<idno type="ISSN">0001-2815</idno>
</seriesStmt>
</fileDesc>
<profileDesc>
<textClass></textClass>
<langUsage>
<language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front>
<div type="abstract">We have updated the catalogue of common and well‐documented (CWD) human leukocyte antigen (HLA) alleles to reflect current understanding of the prevalence of specific allele sequences. The original CWD catalogue designated 721 alleles at the HLA‐A, ‐B, ‐C, ‐DRB1, ‐DRB3/4/5, ‐DQA1, ‐DQB1, and ‐DPB1 loci in IMGT (IMmunoGeneTics)/HLA Database release 2.15.0 as being CWD. The updated CWD catalogue designates 1122 alleles at the HLA‐A, ‐B, ‐C, ‐DRB1, ‐DRB3/4/5, ‐DQA1, ‐DQB1, ‐DPA1 and ‐DPB1 loci as being CWD, and represents 14.3% of the HLA alleles in IMGT/HLA Database release 3.9.0. In particular, we identified 415 of these alleles as being ‘common’ (having known frequencies) and 707 as being ‘well‐documented’ on the basis of ~140,000 sequence‐based typing observations and available HLA haplotype data. Using these allele prevalence data, we have also assigned CWD status to specific G and P designations. We identified 147/151 G groups and 290/415 P groups as being CWD. The CWD catalogue will be updated on a regular basis moving forward, and will incorporate changes to the IMGT/HLA Database as well as empirical data from the histocompatibility and immunogenetics community. This version 2.0.0 of the CWD catalogue is available online at cwd.immunogenomics.org, and will be integrated into the Allele Frequencies Net Database, the IMGT/HLA Database and National Marrow Donor Program's bioinformatics web pages.</div>
</front>
</TEI>
<affiliations>
<list>
<country>
<li>Allemagne</li>
<li>Australie</li>
<li>Autriche</li>
<li>Brésil</li>
<li>Italie</li>
<li>Pays-Bas</li>
<li>Royaume-Uni</li>
<li>République populaire de Chine</li>
<li>Suisse</li>
<li>États-Unis</li>
</country>
<region>
<li>Angleterre</li>
<li>Bade-Wurtemberg</li>
<li>Californie</li>
<li>Canton de Genève</li>
<li>District de Columbia</li>
<li>District de Tübingen</li>
<li>Grand Londres</li>
<li>Lombardie</li>
<li>Utrecht (province)</li>
<li>Vienne (Autriche)</li>
<li>État de São Paulo</li>
</region>
<settlement>
<li>Berkeley (Californie)</li>
<li>Genève</li>
<li>Londres</li>
<li>Los Angeles</li>
<li>Milan</li>
<li>São Paulo</li>
<li>Ulm</li>
<li>Utrecht</li>
<li>Vienne (Autriche)</li>
<li>Washington (district de Columbia)</li>
</settlement>
<orgName>
<li>Université de Genève</li>
</orgName>
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<tree>
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<name sortKey="Mack, S J" sort="Mack, S J" uniqKey="Mack S" first="S. J." last="Mack">S. J. Mack</name>
</noRegion>
<name sortKey="Cano, P" sort="Cano, P" uniqKey="Cano P" first="P." last="Cano">P. Cano</name>
<name sortKey="Fernandez Ina, Marcelo" sort="Fernandez Ina, Marcelo" uniqKey="Fernandez Ina M" first="Marcelo" last="Fernandez-Vina">Marcelo Fernandez-Vina</name>
<name sortKey="Hollenbach, J A" sort="Hollenbach, J A" uniqKey="Hollenbach J" first="J. A." last="Hollenbach">J. A. Hollenbach</name>
<name sortKey="Hurley, C K" sort="Hurley, C K" uniqKey="Hurley C" first="C. K." last="Hurley">C. K. Hurley</name>
<name sortKey="Kempenich, J H" sort="Kempenich, J H" uniqKey="Kempenich J" first="J. H." last="Kempenich">J. H. Kempenich</name>
<name sortKey="Klitz, W" sort="Klitz, W" uniqKey="Klitz W" first="W." last="Klitz">W. Klitz</name>
<name sortKey="Maiers, M" sort="Maiers, M" uniqKey="Maiers M" first="M." last="Maiers">M. Maiers</name>
<name sortKey="Noreen, H" sort="Noreen, H" uniqKey="Noreen H" first="H." last="Noreen">H. Noreen</name>
<name sortKey="Pereira, S E" sort="Pereira, S E" uniqKey="Pereira S" first="S. E." last="Pereira">S. E. Pereira</name>
<name sortKey="Reed, E F" sort="Reed, E F" uniqKey="Reed E" first="E. F." last="Reed">E. F. Reed</name>
<name sortKey="Senitzer, D" sort="Senitzer, D" uniqKey="Senitzer D" first="D." last="Senitzer">D. Senitzer</name>
<name sortKey="Setterholm, M" sort="Setterholm, M" uniqKey="Setterholm M" first="M." last="Setterholm">M. Setterholm</name>
<name sortKey="Smith, A G" sort="Smith, A G" uniqKey="Smith A" first="A. G." last="Smith">A. G. Smith</name>
<name sortKey="Trachtenberg, E" sort="Trachtenberg, E" uniqKey="Trachtenberg E" first="E." last="Trachtenberg">E. Trachtenberg</name>
</country>
<country name="République populaire de Chine">
<noRegion>
<name sortKey="He, J" sort="He, J" uniqKey="He J" first="J." last="He">J. He</name>
</noRegion>
</country>
<country name="Royaume-Uni">
<noRegion>
<name sortKey="Middleton, D" sort="Middleton, D" uniqKey="Middleton D" first="D." last="Middleton">D. Middleton</name>
</noRegion>
<name sortKey="Little, A" sort="Little, A" uniqKey="Little A" first="A." last="Little">A. Little</name>
<name sortKey="Marsh, S G E" sort="Marsh, S G E" uniqKey="Marsh S" first="S. G. E." last="Marsh">S. G. E. Marsh</name>
</country>
<country name="Brésil">
<region name="État de São Paulo">
<name sortKey="Moraes, M E" sort="Moraes, M E" uniqKey="Moraes M" first="M. E." last="Moraes">M. E. Moraes</name>
</region>
<name sortKey="Torres, M" sort="Torres, M" uniqKey="Torres M" first="M." last="Torres">M. Torres</name>
</country>
<country name="Pays-Bas">
<noRegion>
<name sortKey="Tilanus, M G" sort="Tilanus, M G" uniqKey="Tilanus M" first="M. G." last="Tilanus">M. G. Tilanus</name>
</noRegion>
<name sortKey="Rozemuller, E H" sort="Rozemuller, E H" uniqKey="Rozemuller E" first="E. H." last="Rozemuller">E. H. Rozemuller</name>
<name sortKey="Voorter, C E M" sort="Voorter, C E M" uniqKey="Voorter C" first="C. E. M." last="Voorter">C. E. M. Voorter</name>
</country>
<country name="Australie">
<noRegion>
<name sortKey="Varney, M D" sort="Varney, M D" uniqKey="Varney M" first="M. D." last="Varney">M. D. Varney</name>
</noRegion>
<name sortKey="Goodridge, D" sort="Goodridge, D" uniqKey="Goodridge D" first="D." last="Goodridge">D. Goodridge</name>
</country>
<country name="Autriche">
<region name="Vienne (Autriche)">
<name sortKey="Fischer, G F" sort="Fischer, G F" uniqKey="Fischer G" first="G. F." last="Fischer">G. F. Fischer</name>
</region>
</country>
<country name="Italie">
<region name="Lombardie">
<name sortKey="Fleischhauer, K" sort="Fleischhauer, K" uniqKey="Fleischhauer K" first="K." last="Fleischhauer">K. Fleischhauer</name>
</region>
</country>
<country name="Allemagne">
<region name="Bade-Wurtemberg">
<name sortKey="Muller, C R" sort="Muller, C R" uniqKey="Muller C" first="C. R." last="Müller">C. R. Müller</name>
</region>
</country>
<country name="Suisse">
<region name="Canton de Genève">
<name sortKey="Sanchez Azas, A" sort="Sanchez Azas, A" uniqKey="Sanchez Azas A" first="A." last="Sanchez-Mazas">A. Sanchez-Mazas</name>
</region>
</country>
</tree>
</affiliations>
</record>

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